GZA Ziekenhuizen

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https://doi.org/10.1038/nature17676 Landscape of somatic mutations in 560 breast cancer whole-genome sequences
https://doi.org/10.1038/s41577-020-0343-0 COVID-19: the vasculature unleashed
https://doi.org/10.1038/s41591-018-0078-7 Single-cell profiling of breast cancer T cells reveals a tissue-resident memory subset associated with improved prognosis
https://doi.org/10.1016/s1470-2045(14)70069-5 Clinical validity of circulating tumour cells in patients with metastatic breast cancer: a pooled analysis of individual patient data
https://doi.org/10.1097/pap.0000000000000161 Assessing Tumor-Infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method from the International Immuno-Oncology Biomarkers Working Group: Part 2: TILs in Melanoma, Gastrointestinal Tract Carcinomas, Non–Small Cell Lung Carcinoma and Mesothelioma, Endometrial and Ovarian Carcinomas, Squamous Cell Carcinoma of the Head and Neck, Genitourinary Carcinomas, and Primary Brain Tumors
https://doi.org/10.1097/pap.0000000000000162 Assessing Tumor-infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method From the International Immunooncology Biomarkers Working Group: Part 1: Assessing the Host Immune Response, TILs in Invasive Breast Carcinoma and Ductal Carcinoma In Situ, Metastatic Tumor Deposits and Areas for Further Research
https://doi.org/10.1007/s10456-018-9613-x Consensus guidelines for the use and interpretation of angiogenesis assays
https://doi.org/10.1038/s41571-019-0181-9 Vessel co-option in cancer
https://doi.org/10.1126/science.1251343 Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes
https://doi.org/10.1172/jci96313 Spatially distinct tumor immune microenvironments stratify triple-negative breast cancers
https://doi.org/10.1016/j.semcancer.2017.10.003 Update on tumor-infiltrating lymphocytes (TILs) in breast cancer, including recommendations to assess TILs in residual disease after neoadjuvant therapy and in carcinoma in situ: A report of the International Immuno-Oncology Biomarker Working Group on Breast Cancer
https://doi.org/10.1038/ncomms13837 ATR inhibitors as a synthetic lethal therapy for tumours deficient in ARID1A
https://doi.org/10.1172/jci.insight.129641 Tumor-infiltrating B cells signal functional humoral immune responses in breast cancer
https://doi.org/10.1016/j.cmet.2020.03.009 Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis
https://doi.org/10.1038/ncomms11383 The topography of mutational processes in breast cancer genomes
https://doi.org/10.1016/s1470-2045(16)30631-3 Tumour-infiltrating lymphocytes in advanced HER2-positive breast cancer treated with pertuzumab or placebo in addition to trastuzumab and docetaxel: a retrospective analysis of the CLEOPATRA study
https://doi.org/10.1038/modpathol.2016.109 Standardized evaluation of tumor-infiltrating lymphocytes in breast cancer: results of the ring studies of the international immuno-oncology biomarker working group
https://doi.org/10.1016/j.critrevonc.2018.12.004 The clinical use of circulating tumor cells (CTCs) enumeration for staging of metastatic breast cancer (MBC): International expert consensus paper
https://doi.org/10.1080/2162402x.2016.1257452 Tumor-infiltrating lymphocyte composition, organization and PD-1/ PD-L1 expression are linked in breast cancer
https://doi.org/10.1016/j.eururo.2015.07.007 Efficacy of Cabazitaxel in Castration-resistant Prostate Cancer Is Independent of the Presence of AR-V7 in Circulating Tumor Cells
https://doi.org/10.1038/bjc.2017.334 International consensus guidelines for scoring the histopathological growth patterns of liver metastasis
https://doi.org/10.1093/intqhc/mzaa158 COVID-19 is having a destructive impact on health-care workers’ mental well-being
https://doi.org/10.1158/0008-5472.can-12-3931 The Multifaceted Role of the Microenvironment in Liver Metastasis: Biology and Clinical Implications
https://doi.org/10.1111/ner.12738 Muscle Control and Non-specific Chronic Low Back Pain
https://doi.org/10.1007/s00431-021-03968-6 Bronchiolitis in COVID-19 times: a nearly absent disease?
https://doi.org/10.1007/s00234-019-02155-7 The value of four stage vestibular hydrops grading and asymmetric perilymphatic enhancement in the diagnosis of Menière’s disease on MRI
https://doi.org/10.1002/path.4845 Vessel co‐option is common in human lung metastases and mediates resistance to anti‐angiogenic therapy in preclinical lung metastasis models
https://doi.org/10.1186/bcr3127 Expression profiling of cancerous and normal breast tissues identifies microRNAs that are differentially expressed in serum from patients with (metastatic) breast cancer and healthy volunteers
https://doi.org/10.1038/bjc.2013.92 Semiautomated isolation and molecular characterisation of single or highly purified tumour cells from CellSearch enriched blood samples using dielectrophoretic cell sorting
https://doi.org/10.1158/1078-0432.ccr-18-1943 TP53 Outperforms Other Androgen Receptor Biomarkers to Predict Abiraterone or Enzalutamide Outcome in Metastatic Castration-Resistant Prostate Cancer
https://doi.org/10.1093/jnci/djw030 Co-option of Liver Vessels and Not Sprouting Angiogenesis Drives Acquired Sorafenib Resistance in Hepatocellular Carcinoma
https://doi.org/10.1093/bja/aev113 I-AIM framework for point-of-care gastric ultrasound
https://doi.org/10.1038/s41467-022-33052-y Single cell atlas identifies lipid-processing and immunomodulatory endothelial cells in healthy and malignant breast
https://doi.org/10.1172/jci139905 Functional Th1-oriented T follicular helper cells that infiltrate human breast cancer promote effective adaptive immunity
https://doi.org/10.1016/j.eururo.2017.01.011 Comprehensive Profiling of the Androgen Receptor in Liquid Biopsies from Castration-resistant Prostate Cancer Reveals Novel Intra-AR Structural Variation and Splice Variant Expression Patterns
https://doi.org/10.1007/s10456-019-09661-5 Angiogenic desmoplastic histopathological growth pattern as a prognostic marker of good outcome in patients with colorectal liver metastases
https://doi.org/10.1186/s13073-018-0595-5 Cell-free DNA profiling of metastatic prostate cancer reveals microsatellite instability, structural rearrangements and clonal hematopoiesis
https://doi.org/10.18632/oncotarget.3642 PDL1 expression in inflammatory breast cancer is frequent and predicts for the pathological response to chemotherapy
https://doi.org/10.1016/j.radonc.2017.09.001 The long- and short-term variability of breathing induced tumor motion in lung and liver over the course of a radiotherapy treatment
https://doi.org/10.1038/modpathol.2017.43 Reliability of tumor-infiltrating lymphocyte and tertiary lymphoid structure assessment in human breast cancer
https://doi.org/10.1093/jnci/djx268 Immune Infiltration in Invasive Lobular Breast Cancer
https://doi.org/10.3389/fonc.2017.00156 Clinical Validity and Utility of Tumor-Infiltrating Lymphocytes in Routine Clinical Practice for Breast Cancer Patients: Current and Future Directions
https://doi.org/10.1038/ncomms12910 Breast cancer genome and transcriptome integration implicates specific mutational signatures with immune cell infiltration
https://doi.org/10.1016/j.ctrv.2017.04.005 Tumor-infiltrating lymphocytes in patients with HER2-positive breast cancer treated with neoadjuvant chemotherapy plus trastuzumab, lapatinib or their combination: A meta-analysis of randomized controlled trials
https://doi.org/10.1038/ncomms4644 Processed pseudogenes acquired somatically during cancer development
https://doi.org/10.3389/fimmu.2017.01412 Immune Checkpoint Molecules on Tumor-Infiltrating Lymphocytes and Their Association with Tertiary Lymphoid Structures in Human Breast Cancer
https://doi.org/10.1002/cyto.b.20573 External quality assurance of circulating tumor cell enumeration using the CellSearch® system: A feasibility study
https://doi.org/10.1136/esmoopen-2018-000398 Multidisciplinary molecular tumour board: a tool to improve clinical practice and selection accrual for clinical trials in patients with cancer
https://doi.org/10.1172/jci93566 Differential impact of RB status on E2F1 reprogramming in human cancer
https://doi.org/10.1186/bcr3196 The interaction between ER and NFκB in resistance to endocrine therapy
https://doi.org/10.1016/j.celrep.2021.109253 Tumor vessel co-option probed by single-cell analysis
https://doi.org/10.1097/aap.0000000000000510 Analgesic Effect and Functional Improvement Caused by Radiofrequency Treatment of Genicular Nerves in Patients With Advanced Osteoarthritis of the Knee Until 1 Year Following Treatment
https://doi.org/10.1038/s41416-022-01859-7 Histopathological growth patterns of liver metastasis: updated consensus guidelines for pattern scoring, perspectives and recent mechanistic insights
https://doi.org/10.1016/j.radonc.2022.10.005 Recommendations for radiation therapy in oligometastatic prostate cancer: An ESTRO-ACROP Delphi consensus
https://doi.org/10.1016/s2542-5196(20)30059-0 Metal mining and birth defects: a case-control study in Lubumbashi, Democratic Republic of the Congo
https://doi.org/10.1158/0008-5472.can-13-0704 Hallmarks of Aromatase Inhibitor Drug Resistance Revealed by Epigenetic Profiling in Breast Cancer
https://doi.org/10.1038/s41585-022-00670-6 Using PSMA imaging for prognostication in localized and advanced prostate cancer
https://doi.org/10.1111/ner.12741 New Therapy for Refractory Chronic Mechanical Low Back Pain—Restorative Neurostimulation to Activate the Lumbar Multifidus: One Year Results of a Prospective Multicenter Clinical Trial
https://doi.org/10.1007/s10549-018-4834-7 The combined presence of CD20 + B cells and PD-L1 + tumor-infiltrating lymphocytes in inflammatory breast cancer is prognostic of improved patient outcome
https://doi.org/10.1002/cjp2.100 Vascularization of colorectal carcinoma liver metastasis: insight into stratification of patients for anti‐angiogenic therapies
https://doi.org/10.1136/jitc-2019-000313 Efficacy and safety of avelumab treatment in patients with metastatic Merkel cell carcinoma: experience from a global expanded access program
https://doi.org/10.1093/annonc/mds505 A randomized, double-blind, multicenter, phase 2 study of a human monoclonal antibody to human αν integrins (intetumumab) in combination with docetaxel and prednisone for the first-line treatment of patients with metastatic castration-resistant prostate cancer
https://doi.org/10.1158/1078-0432.ccr-21-3017 Assessing CSF ctDNA to Improve Diagnostic Accuracy and Therapeutic Monitoring in Breast Cancer Leptomeningeal Metastasis
https://doi.org/10.1136/esmoopen-2020-000947 Impact of solid cancer on in-hospital mortality overall and among different subgroups of patients with COVID-19: a nationwide, population-based analysis
https://doi.org/10.1016/j.radonc.2018.07.025 Predicting tumour motion during the whole radiotherapy treatment: a systematic approach for thoracic and abdominal lesions based on real time MR
https://doi.org/10.1007/s10456-019-09690-0 Pathological features of vessel co-option versus sprouting angiogenesis
https://doi.org/10.1016/j.cub.2016.01.045 The Initiator Methionine tRNA Drives Secretion of Type II Collagen from Stromal Fibroblasts to Promote Tumor Growth and Angiogenesis
https://doi.org/10.1186/s13613-017-0296-z Emergence of antimicrobial resistance to Pseudomonas aeruginosa in the intensive care unit: association with the duration of antibiotic exposure and mode of administration
https://doi.org/10.1016/j.ydbio.2017.12.001 How glucose, glutamine and fatty acid metabolism shape blood and lymph vessel development
https://doi.org/10.1016/j.canlet.2019.02.027 BRCA gene mutations do not shape the extent and organization of tumor infiltrating lymphocytes in triple negative breast cancer
https://doi.org/10.1016/j.ejca.2022.01.012 Predicting 10-year survival after resection of colorectal liver metastases; an international study including biomarkers and perioperative treatment
https://doi.org/10.1159/000502407 Electrical Vestibular Stimulation in Humans: A Narrative Review
https://doi.org/10.1016/j.molonc.2015.02.006 Decreased expression of ABAT and STC2 hallmarks ER‐positive inflammatory breast cancer and endocrine therapy resistance in advanced disease
https://doi.org/10.1080/2162402x.2021.1929724 Immune landscape of inflammatory breast cancer suggests vulnerability to immune checkpoint inhibitors
https://doi.org/10.1093/jncics/pkab026 Histopathological Growth Patterns and Survival After Resection of Colorectal Liver Metastasis: An External Validation Study
https://doi.org/10.1007/s10456-019-09695-9 Angiotropism, pericytic mimicry and extravascular migratory metastasis: an embryogenesis-derived program of tumor spread
https://doi.org/10.1038/s41416-020-0881-z Enrichment of the tumour immune microenvironment in patients with desmoplastic colorectal liver metastasis
https://doi.org/10.1016/j.ejca.2021.09.003 A phase II study of monalizumab in patients with recurrent/metastatic squamous cell carcinoma of the head and neck: The I1 cohort of the EORTC-HNCG-1559 UPSTREAM trial
https://doi.org/10.1038/s41391-020-00304-1 Automated enumeration and phenotypic characterization of CTCs and tdEVs in patients with metastatic castration resistant prostate cancer
https://doi.org/10.1016/j.ijom.2021.05.015 Patient- and clinician-reported outcomes for the additively manufactured sub-periosteal jaw implant (AMSJI) in the maxilla: a prospective multicentre one-year follow-up study
https://doi.org/10.1093/jnci/djaa113 Serial Analysis of Circulating Tumor Cells in Metastatic Breast Cancer Receiving First-Line Chemotherapy
https://doi.org/10.1002/cjp2.235 Preoperative systemic chemotherapy alters the histopathological growth patterns of colorectal liver metastases
https://doi.org/10.1186/s12943-023-01713-1 Molecular differences of angiogenic versus vessel co-opting colorectal cancer liver metastases at single-cell resolution
https://doi.org/10.1007/s00167-020-06233-9 Resuming elective hip and knee arthroplasty after the first phase of the SARS-CoV-2 pandemic: the European Hip Society and European Knee Associates recommendations
https://doi.org/10.1158/1078-0432.ccr-24-1513 Trastuzumab Deruxtecan with Nivolumab in HER2-Expressing Metastatic Breast or Urothelial Cancer: Analysis of the Phase Ib DS8201-A-U105 Study
https://doi.org/10.1186/s12904-023-01149-w Simulation-based learning in palliative care in postgraduate nursing education: a scoping review
https://doi.org/10.1016/j.xpro.2021.100508 Protocols for endothelial cell isolation from mouse tissues: brain, choroid, lung, and muscle
https://doi.org/10.1016/j.bpa.2023.04.004 Current status of the combined spinal-epidural technique in obstetrics and surgery
https://doi.org/10.1038/s41467-023-40688-x An idiosyncratic zonated stroma encapsulates desmoplastic liver metastases and originates from injured liver
https://doi.org/10.1038/s41467-023-42744-y Paclitaxel plus carboplatin and durvalumab with or without oleclumab for women with previously untreated locally advanced or metastatic triple-negative breast cancer: the randomized SYNERGY phase I/II trial
https://doi.org/10.1002/ejp.2306 European randomized controlled trial evaluating differential target multiplexed spinal cord stimulation and conventional medical management in subjects with persistent back pain ineligible for spine surgery: 24‐month results
https://doi.org/10.1016/j.ctrv.2024.102825 Oral SERDs changing the scenery in hormone receptor positive breast cancer, a comprehensive review
https://doi.org/10.1001/jamaoto.2022.4109 Risk Factors for Hearing Loss at Birth in Newborns With Congenital Cytomegalovirus Infection
https://doi.org/10.1038/s41467-025-56675-3 PPARα-mediated lipid metabolism reprogramming supports anti-EGFR therapy resistance in head and neck squamous cell carcinoma
https://doi.org/10.1016/j.jclinane.2023.111352 High dose glucocorticoids for treatment of postoperative pain: A systematic review of the literature and meta-analysis
https://doi.org/10.1016/j.euo.2023.11.018 A Systematic Review of the Efficacy and Toxicity of Brachytherapy Boost Combined with External Beam Radiotherapy for Nonmetastatic Prostate Cancer
https://doi.org/10.1016/j.ctrv.2024.102865 Efficacy and safety of antibody-drug conjugates in pretreated HER2-low metastatic breast cancer: A systematic review and network meta-analysis
https://doi.org/10.1016/j.esmoop.2024.103691 Real-world treatment patterns and outcomes in patients with HR+/HER2− metastatic breast cancer treated with chemotherapy in the United States
https://doi.org/10.1016/j.nepr.2023.103832 Postgraduate nursing students’ experiences with simulation-based learning in palliative care education: A qualitative study
https://doi.org/10.1093/jnci/djt376 Comparative Proteome Analysis Revealing an 11-Protein Signature for Aggressive Triple-Negative Breast Cancer