HistoGeneX (Belgium)

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JNJ-26854165 - a novel hdm2 antagonist in clinical development showing broad-spectrum preclinical antitumor activity against solid malignancies
https://doi.org/10.1080/23808993.2017.1281737 Digital pathology in immuno-oncology – a roadmap for clinical development
https://doi.org/10.1158/1538-7445.am10-3628 Abstract 3628: JNJ-38877605: A selective oral Met inhibitor for the treatment of cancer
https://doi.org/10.1159/000064514 A Three-Dimensional Quantitative Analysis of Restenosis Parameters after Balloon Angioplasty: Comparison between Semi-Automatic Computer-Assisted Planimetry and Stereology
https://doi.org/10.1016/j.mex.2015.05.002 AutoTag and AutoSnap: Standardized, semi-automatic capture of regions of interest from whole slide images
https://doi.org/10.1158/1538-7445.sabcs20-pd14-06 Abstract PD14-06: Dynamic changes of PD-L1 and T-cell activation in ECLIPSE: A phase II study investigating preoperative immune combination strategies in untreated, operable ER+ primary breast cancer
https://doi.org/10.1136/hrt.2005.086942 Pathological changes in the coronary arteries in the acute coronary syndromes
https://doi.org/10.2746/042516408x278193 Contractile effects of 5‐hydroxytryptamine (5‐HT) in the equine jejunum circular muscle: Functional and immunohistochemical identification of a 5‐HT 1A ‐like receptor
https://doi.org/10.1196/annals.1299.133 Upregulation and Formation of SDS‐Resistant Oligomers of the Proapoptotic Factor Bax in Experimental Atherosclerosis
https://doi.org/10.1369/0022155412470456 Mapping of Carboxypeptidase M in Normal Human Kidney and Renal Cell Carcinoma
https://doi.org/10.1371/journal.pone.0161441 NRP-1 Receptor Expression Mismatch in Skin of Subjects with Experimental and Diabetic Small Fiber Neuropathy
https://doi.org/10.1200/jco.2020.38.15_suppl.e22041 Baseline biomarkers correlated with outcome in advanced melanoma treated with pembrolizumab monotherapy.
https://doi.org/10.1161/circimaging.108.800862 A Histological “Fly-Through” of a Diseased Coronary Artery
https://doi.org/10.1016/j.ejso.2018.10.451 Histopathological growth patterns and positive margins after resection of colorectal liver metastases
https://doi.org/10.1182/blood-2019-123652 Dynamics of Activated CD8+ T-cells and Decreased Osteoclasts in the Tumor Microenvironment are Associated with Clinical Efficacy of Anti-PD-L1 and Anti-CD38 Combination Treatment in Relapsed or Refractory Multiple Myeloma
https://doi.org/10.1038/s41591-020-0923-3 Publisher Correction: Clinical efficacy and biomarker analysis of neoadjuvant atezolizumab in operable urothelial carcinoma in the ABACUS trial
https://doi.org/10.1158/1538-7445.sabcs18-p4-06-08 Abstract P4-06-08: The spatial localization of immune cells predicts prognosis and response to therapy in inflammatory breast cancer
https://doi.org/10.1158/1538-7445.sabcs19-p5-04-04 Abstract P5-04-04: The spatial interactions between FOXP3+ Tregs, CD8+ cytotoxic T cells and tumor cells predict response to therapy and prognosis in inflammatory breast cancer
Quantitative image analysis and flow cytometry can improve early detection of cancer.
https://doi.org/10.1097/01.jto.0000283260.92476.f6 D2-04: MERIT: a prospective study of putative relationships between tumour biomarkers and clinical benefit from erlotinib in advanced non-small cell lung cancer (NSCLC)
https://doi.org/10.1158/1538-7445.mel2014-pr03 Abstract PR03: CD8+ T-cell distribution and immunomodulator expression in BRAF-mutant melanoma affect the response to BRAF inhibitor and chemotherapy
https://doi.org/10.1016/j.vph.2006.08.265 Inhibition of mammalian target of rapamycin selectively clears macrophages in atherosclerotic plaques by autophagy
https://doi.org/10.1016/s1090-3801(09)60427-4 424 FUNCTIONAL RECOVERY PRECEDES STRUCTURAL RECOVERY IN AN EXPERIMENTAL MODEL OF REVERSIBLE SMALL‐FIBER NEUROPATHY USING LASER‐EVOKED POTENTIALS AND SKIN BIOPSY
https://doi.org/10.1109/cic.2008.4749098 An automated approach to quantify volumetric coronary plaque composition by multi-slice computed tomography: An ex-vivo feasibility study
https://doi.org/10.1200/jco.2015.33.15_suppl.e22147 Evaluation of a sensitive and fully automated extended KRAS test for detection of 21 mutations in 6 codons in KRAS exons 2, 3 and 4.
https://doi.org/10.1007/7653_2014_24 Development of Tissue-Based Companion Diagnostics: The Relationship Between the Pharmaceutical Company, Diagnostic Partner, and the Biomarker Laboratory
https://doi.org/10.1158/1538-7445.sabcs16-p2-04-09 Abstract P2-04-09: The prognostic and predictive effect of tumor infiltrating lymphocytes is not determined by B-cells or PD-L1 expression in inflammatory breast cancer
https://doi.org/10.1093/annonc/mdx393.090 The inflamed immune phenotype can be induced by systemic treatment in angiogenic colorectal liver metastases in contrast to non-angiogenic liver metastases
https://doi.org/10.1200/jco.2017.35.15_suppl.e21030 Immune cell profiling of melanoma metastases from patients treated with TriMixDC-MEL dendritic cell therapy in combination with ipilimumab.
https://doi.org/10.1016/j.hpb.2018.06.118 The desmoplastic growth pattern predicts improved survival after resection of colorectal liver metastases
https://doi.org/10.1016/j.hpb.2018.06.315 Intra-metastases and intra-patient single time-frame histopathological growth patterns concordance of resected colorectal liver metastases
https://doi.org/10.1016/j.hpb.2018.06.2590 The relationship between circulating tumour cells and the histopathological growth pattern of resectable colorectal liver metastases
https://doi.org/10.1016/j.ejso.2018.10.452 Histopathological growth patterns impact the efficacy of treatment for recurrent disease in patients with resected colorectal liver metastases
https://doi.org/10.1158/1538-7445.sabcs18-pd9-08 Abstract PD9-08: Breast cancer liver metastases vascularize by vessel co-option, not angiogenesis, and have a desert immune phenotype: A histopathological and gene expression study
https://doi.org/10.1093/annonc/mdz095.030 The spatial relations among immune cells are prognostic in inflammatory breast cancer
https://doi.org/10.1097/01.hs9.0000560768.55763.6b PF620 COMPARISON OF RISS AND IMWG RISK STRATIFICATION GUIDELINES WITH GENE EXPRESSION PROFILE SKY92 IN NEWLY DIAGNOSED MULTIPLE MYELOMA PATIENTS; RESULTS FROM THE PROMMIS TRIAL
https://doi.org/10.1158/1538-7445.sabcs18-2149 Abstract 2149: Association of tumor fusion burden with immune presence and androgen sensitivity in prostate cancer
https://doi.org/10.1016/j.hpb.2019.10.1226 The effect of histopathological growth patterns on recurrence after resection of colorectal liver metastasis.
https://doi.org/10.1200/jco.2020.38.6_suppl.541 MHCI and FOXP3 predicting outcome to neoadjuvant atezolizumab in sequential urothelial cancer tissue.
https://doi.org/10.1158/1538-7445.sabcs19-ot3-18-02 Abstract OT3-18-02: A comparative study of two detection platforms of circulating tumour cells in patients with metastatic breast cancer
Harmonization of Molecular Oncology testing in Belgium: introduction of KRAS testing for colorectal cancer.
https://doi.org/10.1200/jco.2020.38.15_suppl.e18028 Uncovering the immune-modulating role of anti-RANKL therapy for cervical cancer: Preliminary results.
https://doi.org/10.1016/j.urolonc.2020.10.069 CtDNA as a predictor of outcome in patients treated with neoadjuvant atezolizumab in muscle invasive urothelial cancer
https://doi.org/10.1016/j.hpb.2019.10.427 The effect of histopathological growth patterns on recurrence after resection of colorectal liver metastasis
https://doi.org/10.1038/s41591-023-02312-9 Publisher Correction: Clinical efficacy and biomarker analysis of neoadjuvant atezolizumab in operable urothelial carcinoma in the ABACUS trial
https://doi.org/10.5334/ijic.icic23478 Pop-up vaccination as a start for integrated care in Brussels